For the eyes area, Labo Transdermic offers exclusive preparations that are particularly effective for the most frequent needs regarding eye contour, i.e. crow’s feet, dropping eyelids, puffy eyes and dark circles. Lightening Transdermic Care for Periorbital Dark Circles. N-Hydroxysuccinimide and Chrysin activate the removal of blood-originated pigments (bilirubin and iron), responsible for dark circles in the periorbital area.