Synergy Macrola Sachet is an iso-osmotic laxative containing Macrogol 3350 and electrolytes (1 sachet contains 14 gm). Macrogol 3350 in the intestinal lumen collects a large quantity of water which results softening of fecal mass and stimulating natural peristalsis. Macrogol 3350 is not absorbed from the gut and is expelled from the digestive tract unchanged.