Exforge 5mg/160mg Tablet combines two active ingredients: Valsartan and Amlodipine. Valsartan is an angiotensin II receptor blocker (ARB) that works by blocking a substance in the body responsible for constricting blood vessels. This results in relaxed blood vessels, which helps lower blood pressure and increases blood and oxygen flow to the heart. Amlodipine, on the other hand, inhibits the influx of calcium ions across cell membranes, particularly in vascular smooth muscle cells. This leads to vasodilation and a reduction in peripheral vascular resistance, further lowering blood pressure. Exforge 5mg/160mg Tablet is used to treat high blood pressure (hypertension) in adults when either amlodipine or valsartan alone is not enough. High blood pressure can lead to severe health problems like heart disease, and by lowering blood pressure.
